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Fully sequenced samples of complimentary DNA synthesized from single-stranded, non-mammalian RNA. A wide variety of gene inserts are available. Ideal for use in gene cloning, as gene probes, and cDNA library in creation.
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Umibecestat is a small-molecule beta-secretase (BACE-1) inhibitor used for research into Alzheimer's disease. Provided as a research-grade solid for in vitro and preclinical studies, it has formula C19H15ClF7N5O2 and a molecular weight of 513.8 g/mol.
Beta-secretase (BACE-1) inhibitor for Alzheimer's disease research.
High purity suitable for biochemical and cellular assays.
Available in multiple pack sizes, including 50 MG solid vials.
Also available as a 10 mM solution in DMSO for ready-to-use experiments.
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An LPA2 antagonist (IC50 = 17 nM); selective for LPA2 over LPA1 and LPA3 (IC50s = >50 μM); inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells
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This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1.
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Neuromedin U (Human) is a synthetic peptide consisting of the sequence Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2 The molecular weight of this peptide is 3080 4 g/mol and the CAS number is 312306-89-1 This product is for in vitro research use only This product is not for human or animal use
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Rimonabant (SR141716) is a highly potent, brain-penetrated, and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. It also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
Highly potent, brain-penetrated, and selective central cannabinoid receptor (CB1) antagonist
Inhibits mycobacterial membrane protein Large 3 (MMPL3)
Exhibits Ki of 1.8 nM for CB1
Inhibits LPS-induced NO production in BV-2 cells (IC50 = 16.17 μM)
Can inhibit the growth of Mtb with an MIC of 54 μM
Reduced RANTES and MCP-1 serum levels in obese Zucker rats
Slowed weight gain and reduced platelet-bound fibrinogen in obese Zucker rats
Significantly reduced many cardiometabolic risk factors
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